
SEPTERNA INC
SEPNNASDAQTrading Snapshot
- Day Range
- $47.29 β $48.06
- 52-Week Range
- $10.62 β $40.65
- Volume
- $2.80B
- Avg Volume
- $2.73B
- Shares Outstanding
- 45.1M
- Next Earnings
- Oct 19, 2026
Fundamentals Snapshot
- Annual Revenue
- $72M
- Last Q Revenue
- $17M
- P/E Ratio
- β
- P/S Ratio
- 24.2x
- EPS (TTM)
- $-0.82
- Dividend Yield
- β
Why Investors Own SEPN
- βHigh-growth profile β revenue up +42.7% YoY with expanding US Equity exposure.
- βHealthy economics β 37% gross margin and 15% free-cash-flow margin.
- βNew products and segments could unlock additional revenue streams.
Execution delays, intensifying competition, and valuation compression if growth decelerates.
Financial Trends
About SEPTERNA INC
Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products for the treatment of endocrinology, immunology and inflammation, and metabolic diseases. It develops PTH1R Program, oral small molecule Parathyroid Hormone 1 Receptor agonists for the treatment of hypoparathyroidism; SEP-631, an oral small molecule MRGPRX2 negative allosteric modulator (NAM) for chronic spontaneous urticaria and other mast cell diseases; and TSHR Program, an oral small molecule TSHR NAM for gravesβ disease and thyroid eye disease. In addition, it focuses on other therapeutic areas, including neurology, womenβs health, cardiovascular disease, and respiratory disease. It has global collaboration and license agreement with Novo Nordisk to discover, develop and commercialize multiple potential oral small molecule therapies for metabolic-related diseases based on certain specified molecular targets. The company was formerly known as GPCR NewCo, Inc. and changed its name to Septerna Inc. in June 2021. Septerna, Inc. was incorporated in 2019 and is headquartered in South San Francisco, California.
Otter Score Breakdown
βAnalyst Ratings
βLatest News & Updates
Guggenheim Maintains Buy on Septerna, Raises Price Target to $51
Guggenheim analyst Seamus Fernandez maintains Septerna (NASDAQ:SEPN) with a Buy and raises the price target from $45 to $51.
Septerna Q2 EPS $(0.29) Beats $(0.43) Estimate, Sales $26.746M Beat $17.875M Estimate
Septerna (NASDAQ:SEPN) reported quarterly losses of $(0.29) per share which beat the analyst consensus estimate of $(0.43) by 32.56 percent. This is a 48.21 percent increase over losses of $(0.56) per share from the